Staphylococcal endocarditis in rabbits treated with a low dose of cloxacillin

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Staphylococcal endocarditis in rabbits treated with a low dose of cloxacillin.

Rabbits with established staphylococcal endocarditis, injected twice at an interval of 2 h with either 0.5 mg of cloxacillin per kg or saline, were sacrificed 2.5 h after the second injection. Vegetations were excised, weighed, and cultured, and ultrathin sections were prepared and examined by light microscopy, transmission electron microscopy, and scanning electron microscopy. Several affected...

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A case of staphylococcal endocarditis.

Introduction Staphylococcal endocarditis has a very high mortality rate3' 5 and difficulties in its therapy have not been lessened by the emergence of strains of the organism resistant to the commonly used antibiotics. Recently, encouraging reports of the use of vancomycin in resistant staphylococcal infections have appeared." 2, 4 Since the number of patients treated is small, the following ca...

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Staphylococcal Valvular Endocarditis

pREVIOUS reports from this laboratory have described an effective method of producing impairment of cardiac lymph flow in the dog.1-3 One of our dogs, operated upon to produce chronic impairment of cardiac lymph flow, died spontaneously 82 days after surgery. A mediastinal abscess and a vegetative endocarditis of the mitral valve were found at autopsy. The valve changes being a unique occurrenc...

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Staphylococcal Valvular Endocarditis

pREVIOUS reports from this laboratory have described an effective method of producing impairment of cardiac lymph flow in the dog.1-3 One of our dogs, operated upon to produce chronic impairment of cardiac lymph flow, died spontaneously 82 days after surgery. A mediastinal abscess and a vegetative endocarditis of the mitral valve were found at autopsy. The valve changes being a unique occurrenc...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1984

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.25.3.311